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Celada SI, Lim CX, Carisey AF, Ochsner SA, Arce Deza CF, Rexie P, Poli De Frias F, Cardenas-Castillo R, Polverino F, Hengstschläger M, Tsoyi K, McKenna NJ, Kheradmand F, Weichhart T, Rosas IO, Van Kaer L, Celada LJ. Sci Transl Med 2023 Sep 13;15(713):eade2581. SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells. https://doi.org/10.1126/scitranslmed.ade2581 PMID:37703351
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Sipka AS, Chandler TL, Weichhart T, Schuberth HJ, Mann S. Sci Rep 2022 Sep 5;12(1):15084. Inhibition of mTOR in bovine monocyte derived macrophages and dendritic cells provides a potential mechanism for postpartum immune dysfunction in dairy cows. https://doi.org/10.1038/s41598-022-19295-1 PMID:36064574
Sipka A, Weichhart T, Mann S. Vet Immunol Immunopathol. 2022 Jul;249:110441. Pharmacological inhibition of the mTOR pathway alters phenotype and cytokine expression in bovine monocyte-derived dendritic cells. https://doi.org/10.1016/j.vetimm.2022.110441 PMID:35597229
Kraaijvanger R, Seldenrijk K, Beijer E, Damen J, Wilson JL, Weichhart T, Grutters JC, Veltkamp M. Cells 2021 Dec 15;10(12):3545. Activation of Downstream mTORC1 Target Ribosomal Protein S6 Kinase (S6K) Can Be Found in a Subgroup of Dutch Patients with Granulomatous Pulmonary Disease. https://doi.org/110.3390/cells10123545 PMID:34944053
Braun C, Katholnig K, Kaltenecker C, Linke M, Sukhbaatar N, Hengstschläger M, Weichhart T. Cell Stress 2021 Nov 23;5(12):176-182. p38 regulates the tumor suppressor PDCD4 via the TSC-mTORC1 pathway. https://doi.org/10.15698/cst2021.12.260 PMID:34917890
Zhu C, Boucheron N, Müller AC, Májek P, Claudel T, Halilbasic E, Baazim H, Lercher A, Viczenczova C, Hainberger D, Preglej T, Sandner L, Alteneder M, Gülich AF, Khan M, Hamminger P, Remetic J, Ohradanova-Repic A, Schatzlmaier P, Donner C, Fuchs CD, Stojakovic T, Scharnagl H, Sakaguchi S, Weichhart T, Bergthaler A, Stockinger H, Ellmeier W, Trauner M. J Hepatol 2021. Jul 6. 24-NorUrsodeoxycholic acid reshapes immunometabolism in CD8 + T-cells and alleviates hepatic inflammation. https://doi.org/10.1016/j.jhep.2021.06.036 PMID:34242699
Pizzini A, Bacher H, Aichner M, Franchi A, Watzinger K, Tancevski I, Sonnweber T, Mosheimer-Feistritzer B, Duftner C, Zelger B, Pallua J, Sprung S, Weichhart T, Zelger B, Weiss G, Löffler-Ragg J. Respir Med 2021 Jan 5;177:106294. High expression of mTOR signaling in granulomatous lesions is not predictive for the clinical course of sarcoidosis. https://doi.org/10.1016/j.rmed.2020.106294 PMID:33485108
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Calender A, Lim CX, Weichhart T, Buisson A, Besnard V, Rollat-Farnier PA, Bardel C, Roy P, Cottin V, Devouassoux G, Finat A, Pinson S, Lebecque S, Nunes H, Israel-Biet D, Bentaher A, Valeyre D, Pacheco Y; in the frame of GSF (Group Sarcoidosis France). Exome sequencing and pathogenicity-network analysis of 5 French families implicate mTOR signalling and autophagy in familial sarcoidosis. Eur Respir J. 2019. Apr 25. pii: 1900430. https://doi.org/10.1183/13993003.00430-2019 PMID:31023854
Karonitsch T, Kandasamy RK, Kartnig F, Herdy B, Dalwigk K, Niederreiter B, Holinka J, Sevelda F, Windhager R, Bilban M, Weichhart T, Säemann M, Pap T, Steiner G, Smolen JS, Kiener HP, Superti-Furga G. mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation. Cell Rep 2018. 23:2157-2167. https://doi.org/10.1016/j.celrep.2018.04.044 PMID:29768212
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Kopecky C, Michlits G, Säemann MD, Weichhart T. Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity. Cell Metab 2017. 26:2-3. https://doi.org/10.1016/j.cmet.2017.04.007 PMID:28648980
Vijayan V, Srinu T, Karnati S, Garikapati V, Linke M, Kamalyan L, Mali SR, Sudan K, Kollas A, Schmid T, Schulz S, Spengler B, Weichhart T, Immenschuh S, Baumgart-Vogt E. A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide. J Immunol 2017. 198:2414–2425. https://doi.org/10.4049/jimmunol.1601596 PMID:28179495
Kopecky C, Ebtehaj S, Genser B, Drechsler C, Krane V, Antlanger M, Kovarik JJ, Kaltenecker CC, Parvizi M, Wanner C, Weichhart T, Säemann MD, Tietge UJ. HDL Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients. J Am Soc Nephrol 2017. 28:769–775. https://doi.org/10.1681/ASN.2016030262 PMID:27612996
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Genser B, Fischer JE, Figueiredo CA, Alcântara-Neves N, Barreto ML, Cooper PJ, Amorim LD, Saemann MD, Weichhart T, Rodrigues LC. Applied immuno-epidemiological research: an approach for integrating existing knowledge into the statistical analysis of multiple immune markers. BMC Immunol 2016. 17:11. https://doi.org/10.1186/s12865-016-0149-9 PMID:27206492
Üstün S, Lassnig C, Preitschopf A, Mikula M, Müller M, Hengstschläger M, Weichhart T. 2015. Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models. Transpl Immunol 2015. 33:45–50. https://doi.org/10.1016/j.trim.2015.06.001 PMID:26073719
Kopecky C, Genser B, Drechsler C, Krane V, Kaltenecker CC, Hengstschläger M, März W, Wanner C, Säemann MD, Weichhart T. Quantification of HDL proteins, cardiac events, and mortality in patients with type 2 diabetes on hemodialysis. Clin J Am Soc Nephrol 2015. 10:224–231. https://doi.org/10.2215/CJN.06560714 PMID:25424990
Preitschopf A, Li K, Schörghofer D, Kinslechner K, Schütz B, Thi Thanh Pham H, Rosner M, Joo GJ, Röhrl C, Weichhart T, Stangl H, Lubec G, Hengstschläger M, Mikula M. mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression. PLoS One 2014. 9:e107004. https://doi.org/10.1371/journal.pone.0107004 PMID:25221943
Kopecky C, Haidinger M, Birner-Grünberger R, Darnhofer B, Kaltenecker CC, Marsche G, Holzer M, Weichhart T, Antlanger M, Kovarik JJ, Werzowa J, Hecking M, Säemann MD. Restoration of Renal Function Does Not Correct Impairment of Uremic HDL Properties. J Am Soc Nephrol 2015. 26:565-75.https://doi.org/10.1681/ASN.2013111219 PMID:25071090
Fruhwürth S, Krieger S, Winter K, Rosner M, Mikula M, Weichhart T, Bittman R, Hengstschläger M, Stangl H. Inhibition of mTOR Down-regulates Scavenger Receptor, Class B, Type I (SR-BI) Expression, Reduces Endothelial Cell Migration and Impairs Nitric Oxide Production. Biochim Biophys Acta 2014. 1841:944-53. https://doi.org/10.1016/j.bbalip.2014.03.014 PMID:24713582
Haidinger M, Werzowa J, Kain R, Antlanger M, Hecking M, Pfaffenberger S, Mascherbauer J, Gremmel T, Gilbertson JA, Rowczenio D, Weichhart T, Kopecky C, Hörl WH, Hawkins PN, Säemann MD. Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature. Amyloid 2013. 20:72–79. https://doi.org/10.3109/13506129.2013.781998 PMID:23551149
Katholnig K, Kaltenecker CC, Hayakawa H, Rosner M, Lassnig C, Zlabinger GJ, Gaestel M, Müller M, Hengstschläger M, Hörl WH, Park JM, Säemann MD, Weichhart T. p38α senses environmental stress to control innate immune responses via mTOR. J Immunol 2013. 190:1519–1527. https://doi.org/10.4049/jimmunol.1202683 PMID:23315073
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Hecking M, Antlanger M, Winnicki W, Reiter T, Werzowa J, Haidinger M, Weichhart T, Polaschegg HD, Josten P, Exner I, Lorenz-Turnheim K, Eigner M, Paul G, Klauser-Braun R, Hörl WH, Sunder-Plassmann G, Säemann MD. Blood volume-monitored regulation of ultrafiltration in fluid-overloaded hemodialysis patients: study protocol for a randomized controlled trial. Trials 2012. 13:79. https://doi.org/10.1186/1745-6215-13-79 PMID:22682149
Poglitsch M, Weichhart T, Hecking M, Werzowa J, Katholnig K, Antlanger M, Krmpotic A, Jonjic S, Hörl WH, Zlabinger GJ, Puchhammer E, Säemann MD. CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages. Am J Transplant 2012. 12:1458–1468. https://doi.org/10.1111/j.1600-6143.2012.04002.x PMID:22390651
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Atamaniuk J, Kopecky C, Skoupy S, Säemann MD, Weichhart T. Apoptotic cell-free DNA promotes inflammation in haemodialysis patients. Nephrol Dial Transplant 2012. 27:902–905. https://doi.org/10.1093/ndt/gfr695 PMID:22167588
Poglitsch M, Katholnig K, Säemann MD, Weichhart T. Rapid isolation of nuclei from living immune cells by a single centrifugation through a multifunctional lysis gradient. J Immunol Methods 2011. 373:167–173. https://doi.org/10.1016/j.jim.2011.08.012 PMID:21889513
Weichhart T, Haidinger M, Katholnig K, Kopecky C, Poglitsch M, Lassnig C, Rosner M, Zlabinger GJ, Hengstschläger M, Müller M, Hörl WH, Säemann MD. Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells. Blood 2011. 117:4273–4283. https://doi.org/10.1182/blood-2010-09-310888 PMID:21368289
Haidinger M, Werzowa J, Voigt HC, Pleiner J, Stemer G, Hecking M, Döller D, Hörl WH, Weichhart T, Säemann MD. A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation. Trials 2010. 11:91. https://doi.org/10.1186/1745-6215-11-91 PMID:20925938
Haidinger M, Poglitsch M, Geyeregger R, Kasturi S, Zeyda M, Zlabinger GJ, Pulendran B, Hörl WH, Säemann MD, Weichhart T. A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. J Immunol 2010. 185:3919–3931. https://doi.org/10.4049/jimmunol.1000296 PMID:20805416
Wahrmann M, Haidinger M, Körmöczi GF, Weichhart T, Säemann MD, Geyeregger R, Kikić Z, Prikoszovich T, Drach J, Böhmig GA. Effect of the proteasome inhibitor bortezomib on humoral immunity in two presensitized renal transplant candidates. Transplantation 2010. 89:1385–1390. https://doi.org/10.1097/TP.0b013e3181d9e1c0 PMID:20335829
Kiefer FW, Zeyda M, Gollinger K, Pfau B, Neuhofer A, Weichhart T, Säemann MD, Geyeregger R, Schlederer M, Kenner L, Stulnig TM. Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance. Diabetes 2010. 59:935–946. https://doi.org/10.2337/db09-0404 PMID:20107108
Haidinger M, Hecking M, Weichhart T, Poglitsch M, Enkner W, Vonbank K, Prayer D, Geusau A, Oberbauer R, Zlabinger GJ, Soleiman A, Hörl WH, Säemann MD. Sirolimus in renal transplant recipients with tuberous sclerosis complex: clinical effectiveness and implications for innate immunity. Transpl Int 2010. 23:777–785. https://doi.org/10.1111/j.1432-2277.2009.01041.x PMID:20070623
Weichhart T, Brandt O, Lassnig C, Müller M, Hörl WH, Stingl G, Säemann MD. The anti-inflammatory potency of dexamethasone is determined by the route of application in vivo. Immunol Lett 2010. 129:50–52. https://doi.org/10.1016/j.imlet.2009.12.025 PMID:20060857
Haidinger M, Hecking M, Memarsadeghi M, Weichhart T, Werzowa J, Hörl WH, Säemann MD. Late onset Pneumocystis pneumonia in renal transplantation after long-term immunosuppression with belatacept. Transpl Infect Dis 2009. 11:171–174. https://doi.org/10.1111/j.1399-3062.2009.00366.x PMID:19210692
Weichhart T, Costantino G, Poglitsch M, Rosner M, Zeyda M, Stuhlmeier KM, Kolbe T, Stulnig TM, Hörl WH, Hengstschläger M, Müller M, Säemann MD. The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 2008. 29:565–577. https://doi.org/10.1016/j.immuni.2008.08.012 PMID:18848473
Weichhart T, Werzowa J, Hörl WH, Säemann MD. Biological action of rapamycin in renal transplantation. Am J Kidney Dis 2008. 51:531, author reply 531–532. https://doi.org/10.1053/j.ajkd.2007.09.027 PMID:18295073
Kiefer FW, Zeyda M, Todoric J, Huber J, Geyeregger R, Weichhart T, Aszmann O, Ludvik B, Silberhumer GR, Prager G, Stulnig TM. Osteopontin expression in human and murine obesity: extensive local up-regulation in adipose tissue but minimal systemic alterations. Endocrinology 2008. 149:1350–1357. https://doi.org/10.1210/en.2007-1312 PMID:18048491
Pfistershammer K, Klauser C, Leitner J, Stöckl J, Majdic O, Weichhart T, Sobanov Y, Bochkov V, Säemann M, Zlabinger G, Steinberger P. Identification of the scavenger receptors SREC-I, Cla-1 (SR-BI), and SR-AI as cellular receptors for Tamm-Horsfall protein. J Leukoc Biol 2008. 83:131–138. https://doi.org/10.1189/jlb.0407231 PMID:17928461
Haidinger M, Geyeregger R, Poglitsch M, Weichhart T, Zeyda M, Vodenik B, Stulnig TM, Böhmig GA, Hörl WH, Säemann MD. Antithymocyte globulin impairs T-cell/antigen-presenting cell interaction: disruption of immunological synapse and conjugate formation. Transplantation 2007.84:117–121. https://doi.org/10.1097/01.tp.0000266677.45428.80 PMID:17627247
Bobacz K, Sunk IG, Amoyo L, Akira S, Weichhart T, Säemann MD, Smolen JS. Toll-like receptors and chondrocytes: the LPS induced decrease in cartilage mytrix synthesis is dependent on the presence of Toll-like receptor-4 and is antagonized by bone morphogenetic protein-7. Arthritis Rheum 2007. 56:1880–1893. https://doi.org/10.1002/art.22637 PMID:17530716
Huber J, Löffler M, Bilban M, Reimers M, Kadl A, Todoric J, Zeyda M, Geyeregger R, Schreiner M, Weichhart T, Leitinger N, Waldhäusl W, Stulnig TM. Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids. Int J Obes 2007. 31:1004–1013. https://doi.org/10.1038/sj.ijo.0803511 PMID:17130847
Zeyda M, Geyeregger R, Poglitsch M, Weichhart T, Zlabinger GJ, Koyasu S, Hörl WH, Stulnig TM, Watschinger B, Säemann MD. Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-kappaB in immunological synapse formation. J Leukoc Biol 2007. 81:319–327. https://doi.org/10.1189/jlb.0606378 PMID:17038582
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Weichhart T, Horky M, Söllner J, Gangl S, Henics T, Nagy E, Meinke A, von Gabain A, Fraser CM, Gill SR, Hafner M, von Ahsen U. Functional selection of vaccine candidate peptides from Staphylococcus aureus whole-genome expression libraries in vitro. Infect Immun 2003. 71:4633–4641. https://doi.org/10.1128/IAI.71.8.4633-4641.2003 PMID:12874343
Braun C, Weichhart T. mTOR-dependent immunometabolism as Achilles' heel of anticancer therapy. Eur J Immunol 2021 Dec;51(12):3161-3175. https://doi.org/10.1002/eji.202149270 PMID:34648202
Calender A, Weichhart T, Valeyre D, Pacheco Y. Current Insights in Genetics of Sarcoidosis: Functional and Clinical Impacts. J Clin Med 2020. 9(8):E2633. https://doi.org/10.3390/jcm9082633 PMID:32823753
Fritsch SD, Weichhart T. Metabolic and immunologic control of intestinal cell function by mTOR. Int Immunol 2020. 32(7):455-465. https://doi.org/10.1093/intimm/dxaa015 PMID:32140726
Pacheco Y, Lim CX, Weichhart T, Valeyre D, Bentaher A, Calender A. Sarcoidosis and the mTOR, Rac1, and Autophagy Triad. Trends Immunol 2020. 41(4):286-299. https://doi.org/10.1016/j.it.2020.01.007 PMID:32122794
Wilson JL, Mayr HK, Weichhart T. Metabolic Programming of Macrophages: Implications in the Pathogenesis of Granulomatous Disease. Front Immunol. 2019. 10:2265. https://doi.org/10.3389/fimmu.2019.02265 PMID:31681260
Sukhbaatar N, Weichhart T. Iron Regulation: Macrophages in Control. Pharmaceuticals (Basel) 2018. 14;11(4). https://doi.org/10.3390/ph11040137 PMID:30558109
Weichhart T. mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review. Gerontology 2018. 64:127-134. https://doi.org/10.1159/000484629 PMID:29190625
Linke M, Fritsch SD, Sukhbaatar N, Hengstschläger M, Weichhart T. mTORC1 and mTORC2 as regulators of cell metabolism in immunity. FEBS Lett 2017. 591:3089–3103. https://doi.org/10.1002/1873-3468.12711 PMID:28600802
Fritsch S, Weichhart T. Effects of interferons and viruses on metabolism, Frontiers Immunol 2016. 7:630. https://doi.org/10.3389/fimmu.2016.00630 PMID:28066439
Sukhbaatar N, Hengstschläger M, Weichhart T. mTOR-mediated regulation of dendritic cell differentiation and function, Trends Immunol 2016. 37:778-789. https://doi.org/10.1016/j.it.2016.08.009 PMID:27614799
Weichhart T, Hengstschläger M, Linke M. Regulation of innate immune cell function by mTOR. Nat Rev Immunol 2015. 15:599–614. https://doi.org/10.1038/nri3901 PMID:26403194
Duran I, Goebell PJ, Papazisis K, Ravaud A, Weichhart T, Rodriguez-Portal JA, Budde K. Drug-induced pneumonitis in cancer patients treated with mTOR inhibitors: management and insights into possible mechanisms. Expert Opin Drug Saf 2014. 13:361–372. https://doi.org/10.1517/14740338.2014.888056 PMID:24517115
Katholnig K, Linke M, Pham H, Hengstschläger M, Weichhart T. Immune responses of macrophages and dendritic cells regulated by mTOR signalling. Biochem Soc Trans 2013. 41:927–933. https://doi.org/10.1042/BST20130032 PMID:23863158
Haidinger M, Werzowa J, Weichhart T, Säemann MD. Targeting the dysregulated mammalian target of rapamycin pathway in organ transplantation: killing 2 birds with 1 stone. Transplant Rev (Orlando) 2011. 25:145–153. https://doi.org/10.1016/j.trre.2010.11.001 PMID:21419611
Säemann MD, Poglitsch M, Kopecky C, Haidinger M, Hörl WH, Weichhart T. The versatility of HDL: a crucial anti-inflammatory regulator. Eur J Clin Invest 2010. 40:1131–1143. https://doi.org/10.1111/j.1365-2362.2010.02361.x PMID:20695882
Säemann MD, Haidinger M, Hecking M, Hörl WH, Weichhart T. The multifunctional role of mTOR in innate immunity: implications for transplant immunity. Am J Transplant 2009. 9:2655–2661. https://doi.org/10.1111/j.1600-6143.2009.02832.x PMID:19788500
Weichhart T, Säemann MD. The multiple facets of mTOR in immunity. Trends Immunol 2009. 30:218–226. https://doi.org/10.1016/j.it.2009.02.002 PMID:19362054
Weichhart T, Säemann MD. The PI3K/Akt/mTOR pathway in innate immune cells: emerging therapeutic applications. Ann Rheum Dis 2008. 67(Suppl 3):iii70–iii74. https://doi.org/10.1136/ard.2008.098459 PMID:19022819
Weichhart T, Haidinger M, Hörl WH, Säemann MD. Current concepts of molecular defence mechanisms operative during urinary tract infection. Eur J Clin Invest 2008. 38(Suppl 2):29–38. https://doi.org/10.1111/j.1365-2362.2008.02006.x PMID:18826479
Säemann MD, Hörl WH, Weichhart T. Toll-like Rezeptoren und Integrine als Determinanten der Pathogenese des Harnwegsinfekts, Nephro-News 2007. 3/07.
Säemann MD, Weichhart T. Die Bedeutung des unspezifischen Immunsystems für die Nierentransplantation, Nephro-News 2006. 3/06.
Säemann MD, Weichhart T. New insights into the pathogenesis of urinary tract infection. Dtsch Med Wochenschr 2005. 130:2031–2034. https://doi.org/10.1055/s-2005-872625 PMID:16143935
Weichhart T, Zlabinger GJ, Säemann MD. The multiple functions of Tamm-Horsfall protein in human health and disease: a mystery clears up. Wien Klin Wochenschr 2005. 117:316–322. https://doi.org/10.1007/s00508-005-0353-8 PMID:15989109
Säemann MD, Weichhart T, Hörl WH, Zlabinger GJ. Tamm-Horsfall protein: a multilayered defence molecule against urinary tract infection. Eur J Clin Invest 2005. 35:227–235. https://doi.org/10.1111/j.1365-2362.2005.01483.x PMID:15816991
Lim CX, Weichhart T. A fungal antigenic driver for Löfgren's syndrome sarcoidosis. J Exp Med 2021. 218(10):e20211572 https://doi.org/10.1084/jem.20211572 PMID:34515726
Sellares J, Strambu I, Crouser ED, Freudenberg MA, Gulati M, Hart S, Herzog E, Kolb M, Weichhart T, Drake WP, Spitzer G, Singh N, Culver DA. New advances in the development of sarcoidosis models: A synopsis of a symposium sponsored by the Foundation for Sarcoidosis Research. Sarcoidosis Vasc Diffuse Lung Dis 2018. 35 (1) 2-4. http://www.mattioli1885journals.com/index.php/sarcoidosis/article/view/7032
Wilson JL, Weichhart T. TORching a semaphore for alternative macrophage activation. Nat Immunol 2018. 19:512-514 https://doi.org/10.1038/s41590-018-0117-z PMID:29777214
Kopecky C, Weichhart T, Säemann MD. HDL cholesterol efflux capacity and cardiovascular events. N Engl J Med 2015. 372:1869–1872. https://doi.org/10.1056/NEJMc1503139 PMID:25946299
Weichhart T, Säemann MD. Sirolimus and kidney transplantation: unraveling an inflammatory affair. Am J Transplant 2010. 10:2569–2570. https://doi.org/10.1111/j.1600-6143.2010.03306.x PMID:21114639
Weichhart T, Säemann MD. T helper cell differentiation: understanding the needs of hierarchy. Immunity 2010. 32:727–729. https://doi.org/10.1016/j.immuni.2010.06.008 PMID:20620936
Säemann MD, Hörl WH, Weichhart T. Uncovering host defences in the urinary tract: cathelicidin and beyond. Nephrol Dial Transplant 2007. 22:347–349. https://doi.org/10.1093/ndt/gfl590 PMID:17035368
Katholnig K, Poglitsch M, Hengstschläger M, Weichhart T. Lysis gradient centrifugation: a flexible method for the isolation of nuclei from primary cells. Methods Mol Biol 2015. 1228:15–23. https://doi.org/10.1007/978-1-4939-1680-1_2 PMID:25311118
Weichhart T. Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life. Methods Mol Biol 2012. 821:1–14. https://doi.org/10.1007/978-1-61779-430-8_1 PMID:22125056
Editor of “mTOR: Methods and Protocols”, Methods in Molecular Biology, Humana Press, 2012. https://link.springer.com/book/10.1007/978-1-61779-430-8
Thomas Weichhart Lab at the Medical University of Vienna, Center for Pathobiochemistry & Genetics, Vienna, Austria