Metabolic Reprogramming in Granulomatous Diseases

New Review from Jayne and Hannah: "Metabolic Programming of Macrophages: Implications in the Pathogenesis of Granulomatous Disease" published in Frontiers in Immunology (10/2019).

mTOR and sarcoidosis.

New Publication from Clarice and Alain Calender, Yves Pacheco, and  the Group Sarcoidosis France: "Exome sequencing and pathogenicity-network analysis of 5 French families implicate mTOR signalling and autophagy in familial sarcoidosis." published in the European Respiratory Journal (05/2019).

Iron regulation: Macrophages in control

New Review from Nima on the role of macrophages for iron metabolism and erythropoiesis. Published in a special issue of Pharmaceuticals on "Iron as Therapeutic Targets in Human Diseases". (12/2018)

New WWTF Funding

A consortium consisting of Georg Stary (MUV, Department of Dermatology), Thomas Krausgruber (CeMM) and our lab was successful at the last Life Sciences Call 2018 from the WWTF termed "Linking Research & Patients Needs". Georg will coordinate the project termed "Systems medicine analysis of sarcoidosis by targeting mTOR in a co-clinical trial in patients and mice". (10/2018)

Best Oral Presentation Award for Nima

Nima won the award for the best oral presentation at the Congress of the European Macrophage & Dendritic Cell Society (EMDS) in Verona for her presentation on macrophages and iron metabolism. Congrats, Nima! (09/2018)

TORching a semaphore for alternative macrophage activation

News & Views editorial from Jayne on a nice study by Sujin Kang and Atsushi Kumanogoh who link mTORC1 signaling to Semaphorin 6D and metabolic reprogrammig of macrophage polarization. (05/2018)

mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation

New paper out in Cell Reports from Thomas Karonitsch, where our lab had the possibility to contribute to this nice study. (05/2018)

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis

New paper out in BMC Medical Genomics, in which Clarice had the possibility to contribute to this interesting study. (03/2018)

FWF Grant awarded


Our laboratory has been awarded a new FWF Grant from the Austrian Science Fund! (12/2017)

mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review


New review from the lab published in Gerontology entitled "mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review" (12/2017)

Landsteiner Prize for Monika Linke


Monike Linke has won the Landsteiner Prize for the best basic immunological publication with her Nature Immunology paper. Congratulations! (11/2017)

mTORC1 and mTORC2 as regulators of cell metabolism in immunity


New Review from Moni, Stephanie and Nima in a special issue of FEBS Letters: "Immunity and Metabolism"! (06/2017)

Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity


New Article in Cell Metabolism from Chantal describing different acitivites of High-Density Lipoproteins! (06/2017)

Nyamdelger Sukhbaatar receives DOC-Stipendium


Nima received a prestigious DOC-Stipendium of the Austrian Academy of Sciences for her project on macrophages and iron metabolism. Congratulations! (05/2017)

Funding for Creating a Sarcoidosis Model


We obtained funding for the creating, characterizing and improving a mouse model for sarcoidosis from the US-based patient organization "Foundation for Sarcoidosis Research". We are extremely happy and proud to contribute creating novel tools for sarcoidosis research. (04/2017)

How Granulomas forms


Congratulation to Moni and all the others for the new publication in Nature Immunology on how Granulomas forms and develop. Including an editorial from Lalita Ramakrishnan! (03/2017)